Mid-Term Results of Aortic Valve Replacement with Novel “Central Torrent” Mechanical Prosthesis
- #AC/VAL 01-O-8
- Adult Cardiac Surgery/Valves. SESSION-1
- Oral
Mid-Term Results of Aortic Valve Replacement with Novel “Central Torrent” Mechanical Prosthesis
Vladlen Bazylev 1, Eugeny Nemchenko 1, Alisher Gamzaev 2, Igor Chernov 3, Andrey Molchanov 4, Valery Tsehanovich 5, Dmitry Drobot 6, Alexander Bogachev-Prokofyev 7, Dmitry Ananyev 8
1 The Federal State Government-financed Establishment FEDERAL CENTER OF CARDIOVASCULAR SURGERY of the Ministry of Healthcare of Russian Federation (Penza), Penza, Russia; 2 Nizhny Novgorod SCCH, Nizhny Novgorod , Russia; 3 Astrakhan FCCVS, Astrakhan , Russia; 4 Ekaterinburg SRCH, Ekaterinburg , Russia; 5 Omsk RCH, Omsk , Russia; 6 Krasnoyarsk FCCVS, Krasnoyarsk FCCVS, Russia; 7 Novosibirsk NMRC, Novosibirsk , Russia; 8 Barnaul RCH, Barnaul , Russia;
Date, time and location: 2018.05.26 08:30, Congress Hall, 2F–B
Abstract
OBJECTIVE: In contrast to ordinary bileaflet mechanical prosthetic heart valves, leaflets in the
new generation “central torrent” prosthesis in open position are allocated along the inner wall of
its body, forming one almost round orifice. The aim of this study was to analyze mid-term results
of aortic valve replacement (AVR) with “MEDENG-CT”, the first clinically approved “central
torrent” prostheses.
METHODS: Between 2012 and 2017, 154 consequent patients fulfilling inclusion criteria
underwent isolated AVR with “MEDENG-CT” mechanical prostheses in 8 Russian centers.
Clinical data were obtained preoperatively, perioperatively and at discharge. Then mid-term data
were obtained during annual follow-up visits and included blood studies, echocardiography and
examination by the physician.
RESULTS: Mean follow-up time was 25 months (295 pt-yrs), and maximal follow-up time was
61 months. Operative (thirty-day) mortality was 5.8% (9 patients, not valve related). Late
mortality was 0.7%/pt-yrs (1 patient died 4 months post-op, non-cardiac death; 1 patient died 2.5
months post-op during non-cardiac bypass surgery). There were neither reoperations nor cases of
structural dysfunctions, thromboses, pannus formations or major bleedings. There were 3
embolic events (1.9%) in the thirty-day period and 3 late embolic events (1.0%/pt-yrs). Mean
gradient after AVR was 8.5±3.0 mmHg. Peak gradient after AVR was 16.8±5.6 mmHg. INR for
52% of patients was below the recommended level (2.5 – 3.0).
CONCLUSION: “Central torrent” bileaflet mechanical prosthetic heart valve “MEDENG-CT”
shows good mid-term clinical and hemodynamic results even for patients with INR below the
recommended level.